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Factors relating to adherence in HIV-infected women

1. Sayles J et al. J Womens Health 2006;15:173–81
2. Ammassari A, et al. JAIDS 2002;31(Suppl3):S140–4
3. Huang J et al. AIDS Res Ther 2006;3:17
4. Turner B, et al. J Gen Intern Med 2003;18:248–57
5. DiMatteo R, et al. Arch Intern Med 2000; 160: 2101-7
6. Ammassari A, et al. Psychosomatics 2004;45:394–402



Impact of family obligations on adherence in women

1. Ciambrone D, et al. Women Health 2006;44:61–77
2. Roberts KJ & Mann T. AIDS Care 2000;12:377–86



Pill burden and dosing frequency key factors in adherence

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  • Treatment-experienced patients completed a questionnaire that evaluated the impact of perceptions of ten attributes of ART on adherence
  • Total number of pills per day and dosing frequency had the greatest impact on adherence
  • A survey of 20 women with HIV revealed that pill burden was a major barrier to adherence1
  • There is a need for more gender-specific pill-burden data

Adapted from Stone VE, et al. J Acquir Immune Defic Syndr 2004;36:808–16
1. Roberts KJ & Mann T. AIDS Care 2000;12:377–86



Dosing frequency of different ARVs

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Summary of product characteristics available at: http://www.ema.europa.eu. Accessed March 2011.
1. Lopinavir September 2010. Available at: http://www.ema.europa.eu/humandocs/Humans/EPAR/kaletra/kaletra.htm . Accessed March 2011.